รองศาสตราจารย์ ดร.กฤษณ์ชนม์ ภูมิกิตติพิชญ์ รองอธิการบดี มทร.ธัญบุรี เป็นตัวแทนเข้ารับรางวัลโล่เกียรติคุณ สถาบันอุดมศึกษาที่ส่งเสริมการพัฒนาอาจารย์ต้นแบบด้านการสอน
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Evaluation of Haematological and Biochemical Activity of Thai Traditional Antinausea Remedy in Normal Albino rats
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List of authors
Rungnapa Pankla Sranujit 1,*,Chanai Noysang 1, Patcharaporn Tippayawat 2, Nateelak Kooltheat 3, Thitiya Luetragoon 4 and Kanchana Usuwanthim4
1 Faculty of Integrative Medicine, Rajamangala University of Technology Thanyaburi, Pathum Thani 12130, Thailand
2 Center for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Science, Khon Kaen University, Khon Kaen 40002, Thailand
3 Research Excellence Center for Innovation and Health Products, School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand
4 Cellular and Molecular Immunology Research Unit, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok 65000, Thailand
Abstract
This research characterizes phytochemicals inherent in lotus flower and investigates the antioxidant and immunomodulatory activity of ethyl acetate (EA) and ethyl alcohol (ET) lotus petal extracts. In the experiment, human monocytes-derived macrophages were stimulated by lipopolysaccharide to mimic bacteria-induced inflammation. The results showed that ferulic acid, coumarin, and chlorogenic acid were three dominant polyphenols. The EA and ET lotus petal extracts also possessed high antioxidant capability. Furthermore, the extracts exhibited immunomodulatory properties by suppressing TNF-α secretion in inflammatory-induced human macrophages by inhibiting NF-κB-dependent inflammatory response. In essence, the lotus petal extracts possess remedial attributes beneficial to individuals afflicted with declined immune functions. View Full-Text
* Author to whom correspondence should be addressed.
Academic Editor: Marcello Salvatore Lenucci
Plants 2021, 10(10), 2007; https://doi.org/10.3390/plants10102007
